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Article

The evolution of major histocompatibility class I genes in primates.

Critical reviews in immunology - 1 Jan 1995

Watkins D I

Abstract excerpt

MHC class I genes evolve by recombination, largely within loci, and selection (presumably pathogen-driven) maintains these new alleles in the population. Although chimpanzees and humans share an A locus allelic lineage, the B locus molecules of the chimpanzee were less similar to human B locus molecules. The A and B locus molecules in rhesus and cynomolgus monkeys were even less similar to their human...

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PMID: 8519421
DOI: 10.1615/critrevimmunol.v15.i1.10

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