Article
The roles of serum leptin concentration and polymorphism in leptin receptor gene at codon 109 in breast cancer.
Oncology - 1 Jan 2007
Liu Chien-Liang, Chang Yuan-Ching, Cheng Shih-Ping, Chern Schu-Rern, Yang Tsen-Long, Lee Jie-Jen, Guo Ing-Cherng, Chen Chih-Ping
Abstract excerpt
AIMS: We investigated the relationship between serum leptin concentrations and polymorphism of the leptin receptor gene and breast cancer. METHODS: Serum leptin concentrations were measured by enzyme-linked immunosorbent assay in 47 women with invasive breast cancer compared with 41 age-matched controls without cancer. Genomic DNA was extracted from peripheral blood leukocytes. Genotyping of the leptin receptor...
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