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Effect of LEPR Gln223Arg polymorphism on breast cancer risk in different ethnic populations: a meta-analysis.

Molecular biology reports - 1 Mar 2012

He Bang-shun, Pan Yu-qin, Zhang Y, Xu Ye-qiong, Wang Shu-kui

Abstract excerpt

Leptin and leptin receptor have been implicated in processes leading to breast cancer initiation and progression. An A to G transition mutation in codon 223, in exon 6 of the leptin receptor gene (LEPR) can result in glutamine to arginine substitution (Gln223Arg). A variety of case-control studies have been published evaluating the association between LEPR Gln223Arg polymorphism and breast cancer. However,...

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PMID: 21698367
DOI: 10.1007/s11033-011-1076-8

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LEPR

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Effect of LEPR Gln223Arg polymorphism on breast cancer risk in different ethnic populations: a meta-analysis.PMID 21698367Read ↗

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