Article
Association of leptin receptor polymorphisms Lys109Arg and Gln223Arg with serum leptin profile and bone mineral density in Korean women.
American journal of obstetrics and gynecology - 1 Apr 2008
Kim Sun Mie, Kim Seok Hyun, Lee Jung Ryeol, Jee Byung Chul, Ku Seung-Yup, Suh Chang Suk, Choi Young Min, Kim Jung Gu, Moon Shin Yong
Abstract excerpt
OBJECTIVE: The objective of the study was to examine the relationship of the LEPR Lys109Arg and Gln223Arg polymorphisms and the serum leptin profile and bone mineral density (BMD). STUDY DESIGN: Cross-sectional study on a cohort of 145 premenopausal and 118 postmenopausal Korean women. The BMDs and serum levels of leptin, the soluble leptin receptor (sLR), and estradiol were measured, and the LEPR gene was...
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