Article
Correlation of Q223R and K109R polymorphisms in leptin receptor gene with susceptibility of breast cancer: A systematic review and meta-analysis.
Journal of the Chinese Medical Association : JCMA - 1 Jun 2023
Zhu Shaoliang, Tang Zhenyong, Tang Yi, Tan Tingting, Chen Bin, Xie Dongyi, Xie Shaowei, Luo Honglin, Jiang Wenyu, Tang Yuntian, Yang Jianrong
Abstract excerpt
BACKGROUND: Increasing evidence has suggested a strong association of Q223R (rs1137101) and K109R (rs1137100) polymorphisms in leptin receptor (LEPR) gene with susceptibility of breast cancer (BC), but inconsistent results were obtained. To provide a quantitative assessment of this association, a systematic review and meta-analysis was performed. METHODS: A literature search of PubMed, EMBASE, Google Scholar, and...
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