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Article

The association between polymorphisms in the leptin receptor gene and risk of breast cancer: a systematic review and pooled analysis.

Breast cancer research and treatment - 1 Nov 2012

Wang Li-qiang, Shen Wei, Xu Lan, Chen Min-Bin, Gong Ting, Lu Pei-Hua, Tao Guo-Qing

Abstract excerpt

Many epidemiological studies have found that leptin correlates to body fat extent and breast cancer. Leptin exerts its physiological action through the leptin receptor (LEPR). However, published data on the association between LEPR alleles and breast cancer occurrence have led to in contradictory results. A total of 10 studies were identified to the meta-analysis, including 4,644 cases and 5,485 controls for LEPR...

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Alleles
Breast Neoplasms
LEPR gene
Genetic Association Studies
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Receptors, Leptin

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Identifiers

PMID: 22983835
DOI: 10.1007/s10549-012-2228-9

Genes

LEPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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