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Article

Changes in Body Mass Index, Leptin, and Leptin Receptor Polymorphisms and Breast Cancer Risk.

DNA and cell biology - 1 Mar 2018

Liu Chun-Rong, Li Qin, Hou Can, Li Hui, Shuai Ping, Zhao Min, Zhong Xiao-Rong, Xu Zhu-Ping, Li Jia-Yuan

Abstract excerpt

Obesity is a strong risk factor for breast cancer. The polymorphisms of leptin (LEP) and leptin receptor (LEPR) may be associated with breast cancer by regulator of adipose tissue mass and tumor cell growth. A total of 794 cases and 805 matched controls were sequentially enrolled. Time-of-flight mass spectrometry was used to determine the LEPrs7799039, LEPRrs1137100, and LEPRrs1137101 genotypes for each...

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Identifiers

PMID: 29336592
DOI: 10.1089/dna.2017.4047

Genes

LEP
LEPR

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