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Article

SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactions.

Molecular biology of the cell - 1 Feb 2008

Lam Alice D, Tryoen-Toth Petra, Tsai Bill, Vitale Nicolas, Stuenkel Edward L

Abstract excerpt

Membrane fusion is a process that intimately involves both proteins and lipids. Although the SNARE proteins, which ultimately overcome the energy barrier for fusion, have been extensively studied, regulation of the energy barrier itself, determined by specific membrane lipids, has been largely overlooked. Our findings reveal a novel function for SNARE proteins in reducing the energy barrier for fusion, by...

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Identifiers

PMID: 18003982
DOI: 10.1091/mbc.e07-02-0148
PMCID: PMC2230580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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