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Article

Duplex pyrosequencing assay of the 388A>G and 521T>C SLCO1B1 polymorphisms in three Asian populations.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2008

Kim Eun-Young, Cho Doo-Yeoun, Shin Ho-Jung, Lee Sang-Seop, Shon Ji-Hong, Shin Jae-Gook, Shin Sang-Goo

Abstract excerpt

BACKGROUND: We developed a method for detecting important SLCO1B1 polymorphisms and compared the haplotype frequencies in 3 Asian populations. METHODS: We designed a duplex pyrosequencing assay to detect simultaneously the 388A>G and 521T>C variants of SLCO1B1; this method can identify SLCO1B1*1b, SLCO1B1*5, and SLCO1B1*15. The method was validated by direct sequencing of 96 Korean subjects. In addition, duplex...

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PMID: 17996736
DOI: 10.1016/j.cca.2007.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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