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Article

Duplex pyrosequencing of the TPMT3C and TPMT6 alleles in Korean and Vietnamese populations.

Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2008

Lee Sang Seop, Kim Woo-Young, Jang Yin-Jin, Shin Jae-Gook

Abstract excerpt

BACKGROUND: Thiopurine S-methyltransferase (TPMT) genetic polymorphisms have been studied intensively in relation to thiopurine toxicity. In the present study, an improved pyrosequencing method was developed for TPMT genotyping and used to investigate the genotype frequency in Korean and Vietnamese populations. METHODS: Four-hundred Korean and 159 Vietnamese subjects were genotyped by pyrosequencing for TPMT...

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Source

Identifiers

PMID: 18775689
DOI: 10.1016/j.cca.2008.08.014

Genes

TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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