Article
Screening of genetic variations of SLC15A2, SLC22A1, SLC22A2 and SLC22A6 genes.
Journal of human genetics - 1 Sept 2011
Cheong Hyun Sub, Kim Hae Deun, Na Han Sung, Kim Ji On, Kim Lyoung Hyo, Kim Seung Hee, Bae Joon Seol, Chung Myeon Woo, Shin Hyoung Doo
Abstract excerpt
A growing list of membrane-spanning proteins involved in the transport of a large variety of drugs has been recognized and characterized to include peptide and organic anion/cation transporters. Given such an important role of transporter genes in drug disposition process, the role of single-nucleotide polymorphisms (SNPs) in such transporters as potential determinants of interindividual variability in drug...
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