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Article

Neuronal binucleation in Alzheimer disease hippocampus

14 Nov 2007

Abstract excerpt

AIMS: The literature and teachings instruct that neurones in the adult brain are fully differentiated, quiescent cells that never divide. Somewhat surprisingly, and counter to such dogma, susceptible neurones in Alzheimer disease display an activated cell cycle phenotype. However, whether this leads to a coordinated procession through the cell cycle is unclear, particularly whether neurones enter anaphase and...

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PMID: 17995921
DOI: 10.1111/j.1365-2990.2007.00908.x

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