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Article

Aneuploidy, chromosomal missegregation, and cell cycle reentry in Alzheimer's disease.

Acta neurobiologiae experimentalis - 1 Jan 2009

Zekanowski Cezary, Wojda Urszula

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disorder with a complex etiology and pathogenesis. Chromosome missegregation was proposed two decades ago to be responsible for neurodegeneration in AD patients. It was speculated that the aneuploidy is a result of aberrant cell cycle of neuronal progenitors during adult neurogenesis and/or of mature neurons. There is mounting evidence of increased rate of general...

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Identifiers

PMID: 19593337
DOI: 10.55782/ane-2009-1748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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