Article
Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability.
Neuroscience and biobehavioral reviews - 1 Aug 2015
Bajic Vladan, Spremo-Potparevic Biljana, Zivkovic Lada, Isenovic Esma R, Arendt Thomas
Abstract excerpt
Neurons are postmitotic cells that are in permanent cell cycle arrest. However, components of the cell cycle machinery that are expressed in Alzheimer's disease (AD) neurons are showing features of a cycling cell and those attributed to a postmitotic cell as well. Furthermore, the unique physiological operations taking place in neurons, ascribed to "core cell cycle regulators" are also key regulators in cell...
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