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Review: Cell cycle aberrations and neurodegeneration

6 Jan 2010

Abstract excerpt

The cell cycle is a highly regulated and fundamental cellular process that involves complex feedback regulation of many proteins, and any compromise to its integrity elicits dire consequences for the cell. For example, in neurodegenerative diseases such as Alzheimer disease (AD), evidence for abnormal cell cycle re-entry precedes other hallmarks of disease and as such, implicates cell cycle aberrations in the...

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PMID: 20059701
DOI: 10.1111/j.1365-2990.2010.01064.x

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