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Article

The role of cell cycle‐mediated events in Alzheimer's disease

1 Apr 1999

Abstract excerpt

The mechanism(s) underlying selective neuronal death in Alzheimer's disease remain unresolved. However, recently, we and others showed that susceptible hippocampal neurones in Alzheimer's disease express markers common to cells in various phases of the cell cycle. Since neuronal maturation is associated with effective escape from the cell division cycle, emergence out of quiescence may be deleterious. Here, we...

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PMID: 10469261
DOI: 10.1046/j.1365-2613.1999.00106.x

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