Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria.

The American journal of pathology - 1 Dec 2007

Lovegrove Fiona E, Gharib Sina A, Patel Samir N, Hawkes Cheryl A, Kain Kevin C, Liles W Conrad

Abstract excerpt

Specific local brain responses, influenced by parasite sequestration and host immune system activation, have been implicated in the development of cerebral malaria. This study assessed whole-brain transcriptional responses over the course of experimental cerebral malaria by comparing genetically resistant and susceptible inbred mouse strains infected with Plasmodium berghei ANKA. Computational methods were used...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Brain Chemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Interferons

Share to Malaria, Cerebral

Share to Mice, Inbred Strains

Share to Oligonucleotide Array Sequence Analysis

Share to Plasmodium berghei

Source

Open in PubMed Open full text

Identifiers

PMID: 17991715
DOI: 10.2353/ajpath.2007.070630
PMCID: PMC2111112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria.PMID 17991715Read ↗

Gene-expression profiling discriminates between cerebral malaria (CM)-susceptible mice and CM-resistant mice.Semantic proximity Read ↗

Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice.Semantic proximity Read ↗

Simultaneous host and parasite expression profiling identifies tissue-specific transcriptional programs associated with susceptibility or resistance to experimental cerebral malariaSemantic proximity Read ↗

The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression and after artemisinin treatmentSemantic proximity Read ↗

Molecular correlates of experimental cerebral malaria detectable in whole blood.Semantic proximity Read ↗

Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malariaSemantic proximity Read ↗

Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral MalariaSemantic proximity Read ↗

Transcriptional Profiling Reveals Suppressed Erythropoiesis, Up‐Regulated Glycolysis, and Interferon‐Associated Responses in Murine MalariaSemantic proximity Read ↗

Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malariaSemantic proximity Read ↗

Profiles of cytokine production in relation with susceptibility to cerebral malaria.Semantic proximity Read ↗

Pathogenic roles of CD14, galectin-3, and OX40 during experimental cerebral malaria in mice.Semantic proximity Read ↗

Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malariaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.