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Transcriptional Profiling Reveals Suppressed Erythropoiesis, Up‐Regulated Glycolysis, and Interferon‐Associated Responses in Murine Malaria

22 Mar 2004

Abstract excerpt

The primary pathophysiological events contributing to fatal malaria are the cerebral syndrome, anemia, and lactic acidosis. The molecular basis of each event has been unclear. In the present study, microarray analysis of murine transcriptional responses during the development of severe disease revealed temporal, organ-specific, and pathway-specific patterns. More than 400 genes in the brain and 600 genes in the...

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PMID: 15031794
DOI: 10.1086/382596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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