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Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria

19 Dec 2016

Abstract excerpt

Cerebral malaria is a pathology involving inflammation in the brain. There are many immune cell types activated during this process, but there is little information on the response of microglia, in this severe complication. We examined microglia by genome wide transcriptomic analysis in a model of experimental cerebral malaria (ECM), in which C57BL/6 mice are infected with Plasmodium berghei ANKA. Thousands of...

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PMID: 27991544
DOI: 10.1038/srep39258

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