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Article

Estimating the relative contribution of dNTP pool imbalance and APOBEC3G/3F editing to HIV evolution in vivo.

Journal of computational biology : a journal of computational molecular cell biology - 1 Oct 2007

Deforche Koen, Camacho Ricardo, Laethem Kristel Van, Shapiro Beth, Moreau Yves, Rambaut Andrew, Vandamme Anne-Mieke, Lemey Philippe

Abstract excerpt

The human immunodeficiency virus (HIV) has a genome that is rich in adenine, and its rapid evolution shows an observed bias of guanine (G) to adenine (A) mutations. Two mechanisms have been proposed to explain these properties: (1) an imbalance in dNTP pool concentrations which drives the misinco...

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Identifiers

PMID: 17985990
DOI: 10.1089/cmb.2007.0073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17985990-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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