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Article

Spontaneous atherothrombosis and medial degradation in Apoe-/-, Npc1-/- mice.

Circulation - 20 Nov 2007

Welch Carrie L, Sun Yu, Arey Brian J, Lemaitre Vincent, Sharma Naresh, Ishibashi Minako, Sayers Scott, Li Rong, Gorelik Anna, Pleskac Nick, Collins-Fletcher Kadesha, Yasuda Yoshiyuki, Bromme Dieter, D'Armiento Jeanine M, Ogletree Martin L, Tall Alan R

Abstract excerpt

BACKGROUND: The formation of an occluding thrombus on a ruptured or eroded atherosclerotic plaque is the hallmark event leading to acute coronary syndromes, myocardial infarction, and sudden death in humans. However, other species are highly resistant to plaque complications, and the specific processes predisposing to plaque destabilization and thrombosis are poorly understood. METHODS AND RESULTS: Mice carrying...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17984379
DOI: 10.1161/CIRCULATIONAHA.107.701276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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