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Article

A dominant negative mutant of Bacillus anthracis protective antigen inhibits anthrax toxin action in vivo.

The Journal of biological chemistry - 22 Jun 2001

Singh Y, Khanna H, Chopra A P, Mehra V

Abstract excerpt

PA63, a proteolytically activated 63-kDa form of anthrax protective antigen (PA), forms heptameric oligomers and has the ability to bind and translocate the catalytic moieties, lethal factor (LF), and edema factor (EF) into the cytosol of mammalian cells. Acidic pH triggers oligomerization and me...

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Identifiers

PMID: 11278644
DOI: 10.1074/jbc.M010222200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11278644-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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