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Article

Eczema genetics: current state of knowledge and future goals.

The Journal of investigative dermatology - 1 Mar 2009

Brown Sara J, McLean W H Irwin

Abstract excerpt

Multiple genetic as well as environmental factors interact in the pathogenesis of eczema. Increased understanding of genetic predisposition in atopy and eczema has directed interest toward key pathogenic mechanisms including skin barrier dysfunction. This review provides a succinct update on the current state of knowledge regarding eczema genetics. We discuss the relevance of loss-of-function mutations in the...

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Identifiers

PMID: 19209157
DOI: 10.1038/jid.2008.413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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