Article
Selecting predictive markers for pharmacogenetic traits: tagging vs. data-mining approaches.
Human heredity - 1 Jan 2008
Sabbagh Audrey, Génin Emmanuelle, Darlu Pierre
Abstract excerpt
OBJECTIVE: The tagging approach appears as a promising tool to test the association of genetic variants with complex traits such as disease susceptibility or drug response. However, since tag markers are selected only on the basis of inter-marker LD properties, regardless of any phenotypes, it remains unclear to what extent they can be useful to predict variable drug responses, once typed in clinical material. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
