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Article

Identification of prostate cancer modifier pathways using parental strain expression mapping.

Proceedings of the National Academy of Sciences of the United States of America - 6 Nov 2007

Xu Qing, Majumder Pradip K, Ross Kenneth, Shim Yeonju, Golub Todd R, Loda Massimo, Sellers William R

Abstract excerpt

Inherited genetic risk factors play an important role in cancer. However, other than the Mendelian fashion cancer susceptibility genes found in familial cancer syndromes, little is known about risk modifiers that control individual susceptibility. Here we developed a strategy, parental strain expression mapping, that utilizes the homogeneity of inbred mice and genome-wide mRNA expression analyses to directly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17978178
DOI: 10.1073/pnas.0708476104
PMCID: PMC2077015

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AKT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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