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Article

In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2015

Hadsell Darryl L, Hadsell Louise A, Olea Walter, Rijnkels Monique, Creighton Chad J, Smyth Ian, Short Kieran M, Cox Liza L, Cox Timothy C

Abstract excerpt

Genetic background plays a dominant role in mammary gland development and breast cancer (BrCa). Despite this, the role of genetics is only partially understood. This study used strain-dependent variation in an inbred mouse mapping panel, to identify quantitative trait loci (QTL) underlying structural variation in mammary ductal development, and determined if these QTL correlated with genomic intervals conferring...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25552398
DOI: 10.1007/s00335-014-9551-x
PMCID: PMC4548818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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