Article
The genetics of cancer susceptibility: from mouse to man.
Toxicologic pathology - 1 Jan 2000
Ewart-Toland Amanda, Balmain Allan
Abstract excerpt
Cancer affects approximately 1 in 3 individuals. An individual's susceptibility to cancer is partly determined by environmental exposures and by the combination of inherited cancer susceptibility and resistance genes. Initial mapping of these low penetrance cancer susceptibility genes has been done in the mouse because human low penetrance genes are extremely difficult to find using traditional methods due to...
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