Article
Global expression profiling and pathway analysis of mouse mammary tumor reveals strain and stage specific dysregulated pathways in breast cancer progression.
Cell cycle (Georgetown, Tex.) - 1 Jan 2018
Mei Yan, Yang Jun-Ping, Lang Yan-Hong, Peng Li-Xia, Yang Ming-Ming, Liu Qing, Meng Dong-Fang, Zheng Li-Sheng, Qiang Yuan-Yuan, Xu Liang, Li Chang-Zhi, Wei Wen-Wen, Niu Ting, Peng Xing-Si, Yang Qin, Lin Fen, Hu Hao, Xu Hong-Fa, Huang Bi-Jun, Wang Li-Jing, Qian Chao-Nan
Abstract excerpt
It is believed that the alteration of tissue microenvironment would affect cancer initiation and progression. However, little is known in terms of the underlying molecular mechanisms that would affect the initiation and progression of breast cancer. In the present study, we use two murine mammary tumor models with different speeds of tumor initiation and progression for whole genome expression profiling to reveal...
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