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Methods to study xenografted human cancer in genetically diverse mice

2024-01-25

Abstract excerpt

<h4>ABSTRACT</h4> Xenografting human cancer tissues into mice to test new cures against cancers is critical for understanding and treating the disease. However, only a few inbred strains of mice are used to study cancers, and derivatives of mainly one strain, mostly NOD/ShiLtJ, are used for therapy efficacy studies. As it has been demonstrated when human cancer cell lines or patient-derived tissues (PDX) are xeno...

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Literature Corpus work
358b44a6-af3e-5aa2-b71c-691a6f2b23a8
DOI
10.1101/2024.01.23.576906
Open publication

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Methods to study xenografted human cancer in genetically diverse miceDOI 10.1101/2024.01.23.576906
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