Article
Variations in the UDP-glucuronosyltransferase 1A1 gene for the development of unconjugated hyperbilirubinemia in Taiwanese.
Pharmacogenomics - 1 Sept 2008
Huang Yang-Yang, Huang May-Jen, Yang Sieng-Sien, Teng Hsiu-Chen, Huang Ching-Shan
Abstract excerpt
INTRODUCTION: Results of several studies have indicated that the variation of c.-3279T>G in the UDP-glucuronosyltransferase (UGT)1A1 gene could be a further factor for the development of hyperbilirubinemia. However, this variant has not been reported in the Taiwanese population. MATERIALS & METHODS: PCR-restriction fragment length polymorphism was utilized to determine variants at nucleotides -3279 (*60), -53...
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