Article
Genetic factors related to unconjugated hyperbilirubinemia amongst adults.
Pharmacogenetics and genomics - 1 Jan 2005
Huang Ching-Shan, Huang May-Jen, Lin Min-Shung, Yang Sien-Sing, Teng Hsiu-Chen, Tang Kung-Sheng
Abstract excerpt
Some variations in the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene are involved in the development of unconjugated hyperbilirubinemia. We hypothesize that other genetic factors may also be associated with this disease. A total of 227 adults with normal routine haematology and liver function (apart from bilirubin testing for which they revealed bilirubin > or = 25.7 micromol/l and unconjugated bilirubin/total...
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