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Article

The Wegener's granulomatosis quantitative trait locus on chromosome 6p21.3 as characterised by tagSNP genotyping.

Annals of the rheumatic diseases - 1 Jul 2008

Heckmann M, Holle J U, Arning L, Knaup S, Hellmich B, Nothnagel M, Jagiello P, Gross W L, Epplen J T, Wieczorek S

Abstract excerpt

BACKGROUND: A genomic region on chromosome 6p21.3, including HLA-DPB1, has been linked to Wegener's granulomatosis (WG). The basis of this association is difficult to evaluate because of the complex haplotype block architecture of this region. OBJECTIVE: To identify the causative molecular genetic variation(s) using a detailed HapMap based fine-mapping approach. METHODS: 282 patients with WG and 380 healthy...

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Share to Antibodies, Antineutrophil Cytoplasmic
Share to Chromosomes, Human, Pair 6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Granulomatosis with Polyangiitis

Share to Histocompatibility Testing

Share to HLA-DP Antigens

Share to HLA-DP beta-Chains

Share to Polycomb Repressive Complex 1

Share to Quantitative Trait Loci

Source

Identifiers

PMID: 17967832
DOI: 10.1136/ard.2007.077693

Genes

RING1
RXRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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