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Article

Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells.

PLoS pathogens - 26 Oct 2007

Yamashita Masahiro, Perez Omar, Hope Thomas J, Emerman Michael

Abstract excerpt

HIV and other lentiviruses can productively infect nondividing cells, whereas most other retroviruses, such as murine leukemia virus, require cell division for efficient infection. However, the determinants for this phenotype have been controversial. Here, we show that HIV-1 capsid (CA) is involved in facilitating HIV infection of nondividing cells because amino acid changes on CA severely disrupt the cell-cycle...

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Identifiers

PMID: 17967060
DOI: 10.1371/journal.ppat.0030156
PMCID: PMC2042020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells.PMID 17967060Read ↗

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