Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Cell Cycle Independence of HIV Infections Is Not Determined by Known Karyophilic Viral Elements

7 Nov 2005

Abstract excerpt

Human immunodeficiency virus and other lentiviruses infect cells independent of cell cycle progression, but gammaretroviruses, such as the murine leukemia virus (MLV) require passage of cells through mitosis. This property is thought to be important for the ability of HIV to infect resting CD4+ T cells and terminally differentiated macrophages. Multiple and independent redundant nuclear localization signals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16292356
DOI: 10.1371/journal.ppat.0010018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Cell Cycle Independence of HIV Infections Is Not Determined by Known Karyophilic Viral ElementsPMID 16292356Read ↗

Identification of critical amino acid residues in human immunodeficiency virus type 1 IN required for efficient proviral DNA formation at steps prior to integration in dividing and nondividing cells.Semantic proximity Read ↗

The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.Semantic proximity Read ↗

Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and ReplicationSemantic proximity Read ↗

Nuclear Import of the Pre-Integration Complex (PIC): The Achilles Heel of HIV ?Semantic proximity Read ↗

Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import.Semantic proximity Read ↗

Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus.Semantic proximity Read ↗

Evaluation of the Functional Involvement of Human Immunodeficiency Virus Type 1 Integrase in Nuclear Import of Viral cDNA during Acute InfectionSemantic proximity Read ↗

The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes.Semantic proximity Read ↗

Comparative Analysis of HIV-1 and Murine Leukemia Virus Three-Dimensional Nuclear DistributionsSemantic proximity Read ↗

Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex.Semantic proximity Read ↗

HumanImmunodeficiency Virus Type 1 DNA Nuclear Import and Integration AreMitosis Independent in CyclingCellsSemantic proximity Read ↗

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.