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Article

Lv2, a Novel Postentry Restriction, Is Mediated by both Capsid and Envelope

27 Jan 2004

Abstract excerpt

The characterization of restrictions to lentivirus replication in cells identifies critical steps in the viral life cycle and potential therapeutic targets. We previously reported that a human immunodeficiency virus type 2 (HIV-2) isolate was restricted to infection in some human cells, which led us to identify a step in the life cycle of HIV-2 detected after reverse transcription but prior to nuclear entry. The...

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PMID: 14747565
DOI: 10.1128/jvi.78.4.2006-2016.2004

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