Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia.

Arthritis research & therapy - 1 Jan 2007

Vargas-Alarcón Gilberto, Fragoso José-Manuel, Cruz-Robles David, Vargas Angélica, Vargas Alfonso, Lao-Villadóniga José-Ignacio, García-Fructuoso Ferrán, Ramos-Kuri Manuel, Hernández Fernando, Springall Rashidi, Bojalil Rafael, Vallejo Maite, Martínez-Lavín Manuel

Abstract excerpt

Autonomic dysfunction is frequent in patients with fibromyalgia (FM). Heart rate variability analyses have demonstrated signs of ongoing sympathetic hyperactivity. Catecholamines are sympathetic neurotransmitters. Catechol-O-methyltransferase (COMT), an enzyme, is the major catecholamine-clearing pathway. There are several single-nucleotide polymorphisms (SNPs) in the COMT gene associated with the different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catechol O-Methyltransferase
Share to Fibromyalgia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to Hispanic or Latino

Share to Mexican Americans

Share to Mexico

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 17961261
DOI: 10.1186/ar2316
PMCID: PMC2212567

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia.PMID 17961261Read ↗

Association between catechol-O-methyl transferase gene polymorphisms and fibromyalgia in a Korean population: A case-control study.Semantic proximity Read ↗

Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene.Semantic proximity Read ↗

Association of polymorphism of the enzyme catechol-o-methyltransferase with fibromialgic syndrome and its clinical repercussionsSemantic proximity Read ↗

Influence of catechol-O-methyltransferase (COMT) gene polymorphisms in pain sensibility of Brazilian fibromialgia patients.Semantic proximity Read ↗

UNRAVELING THE CLINICO-GENETIC ASSOCIATION OF CATECHOL-O-METHYLTRANSFERASE-RS4680 G>A GENE POLYMORPHISM IN WOMEN WITH FIBROMYALGIA SYNDROME.Semantic proximity Read ↗

The relationship between a common catechol-O-methyltransferase (COMT) polymorphism val(158) met and fibromyalgia.Semantic proximity Read ↗

The polymorphism Val158Met in the COMT gene: disrupted dopamine system in fibromyalgia patients?Semantic proximity Read ↗

Association between the COMT Val158Met polymorphism and fibromyalgia susceptibility and fibromyalgia impact questionnaire score: a meta-analysis.Semantic proximity Read ↗

Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility.Semantic proximity Read ↗

Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism.Semantic proximity Read ↗

Catechol-O-methyltransferase Val158Met polymorphism influences anxiety, depression, and disability, but not pressure pain sensitivity, in women with fibromyalgia syndrome.Semantic proximity Read ↗

Genetic and epigenetic regulation of Catechol-O-methyltransferase in relation to inflammation in chronic fatigue syndrome and Fibromyalgia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.