Article
Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility.
Rheumatology international - 1 May 2008
Tander Berna, Gunes Sezgin, Boke Omer, Alayli Gamze, Kara Nurten, Bagci Hasan, Canturk Ferhan
Abstract excerpt
Genetic and environmental factors are thought to play roles in the etiopathology of fibromyalgia syndrome (FMS). The objective of this study was to determine the potential effects of single nucleotide polymorphisms (SNPs) in catechol-O-methyltransferase (COMT) (rs4680) and 5-hydroxytryptamine (serotonin) 2A (5-HT2A) receptor (rs6313 and rs6311) genes on susceptibility to FMS. One hundred seventy-one women (80...
Read the complete abstract on PubMed