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Article

Influence of catechol-O-methyltransferase (COMT) gene polymorphisms in pain sensibility of Brazilian fibromialgia patients.

Rheumatology international - 1 Feb 2012

Barbosa Flávia Regina, Matsuda Josie Budag, Mazucato Mendelson, de Castro França Suzelei, Zingaretti Sônia Marli, da Silva Lucienir Maria, Martinez-Rossi Nilce Maria, Júnior Milton Faria, Marins Mozart, Fachin Ana Lúcia

Abstract excerpt

Fibromyalgia syndrome (FS) is a rheumatic syndrome affecting to 2-3% of individuals of productive age, mainly women. Neuroendocrine and genetic factors may play a significant role in development of the disease which is characterized by diffuse chronic pain and presence of tender points. Several studies have suggested an association between FS, especially pain sensitivity, and polymorphism of the...

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PMID: 21120493
DOI: 10.1007/s00296-010-1659-z

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of catechol-O-methyltransferase (COMT) gene polymorphisms in pain sensibility of Brazilian fibromialgia patients.PMID 21120493Read ↗

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