Article
Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene.
European journal of pain (London, England) - 1 Jan 2013
Martínez-Jauand M, Sitges C, Rodríguez V, Picornell A, Ramon M, Buskila D, Montoya P
Abstract excerpt
BACKGROUND: Recent evidence suggests that genetic factors might contribute to individual differences in pain sensitivity, risk for developing clinical pain conditions and efficacy of pain treatments. The purpose of the present study was to investigate the relationship of three common haplotypes of COMT gene affecting the metabolism of catecholamines on pain sensitivity in patients with fibromyalgia (FM). METHODS:...
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