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Association between catechol-O-methyl transferase gene polymorphisms and fibromyalgia in a Korean population: A case-control study.

European journal of pain (London, England) - 1 Aug 2016

Park D J, Kim S H, Nah S S, Lee J H, Kim S K, Lee Y A, Hong S J, Kim H S, Lee H S, Kim H A, Joung C I, Kim S H, Lee S S

Abstract excerpt

BACKGROUND: Although polymorphisms of the catechol-O-methyl transferase (COMT) gene have been implicated in altered pain sensitivity, results concerning the association between COMT gene polymorphisms and fibromyalgia (FM) are equivocal. We assessed the associations between COMT single-nucleotide polymorphisms (SNP) and FM risk and symptom severity. METHODS: In total, 409 FM patients and 423 controls were...

Topics

Adult
Asian People
Case-Control Studies
Catechol O-Methyltransferase
Female
Fibromyalgia
Genotype
Humans
Male
Middle Aged
Pain Threshold

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Republic of Korea

Source

Identifiers

PMID: 26849490
DOI: 10.1002/ejp.837

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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