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Article

Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations.

Genes and immunity - 1 Jan 2008

Zhu G, Carlsen K, Carlsen K-H, Lenney W, Silverman M, Whyte M K, Hosking L, Helms P, Roses A D, Hay D W, Barnes M R, Anderson W H, Pillai S G

Abstract excerpt

Endothelin-1 (EDN1) has been reported to be implicated in the pathophysiology of asthma. Literature results on the genetic association of EDN1 in asthma are inconsistent. Eleven single nucleotide polymorphisms in EDN1 were genotyped in 342 and 100 families from UK and Norway, respectively. Asthma, bronchial hyperreactivity (BHR) and atopic asthma phenotypes were analyzed for the family-based association. Five...

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Identifiers

PMID: 17960156
DOI: 10.1038/sj.gene.6364441

Genes

EDN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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