Article
Association of PTGDR gene polymorphisms with asthma in two Caucasian populations.
Genes and immunity - 1 Jul 2007
Zhu G, Vestbo J, Lenney W, Silverman M, Whyte M, Helms P, Anderson W H, Pillai S G
Abstract excerpt
The prostanoid DP receptor (PTGDR) is shown to be involved in the asthma patho-physiology and the results from the published genetic association studies are inconsistent. Four single nucleotide polymorphisms (SNPs) in PTGDR were genotyped in 342 and 294 families from UK and Denmark respectively. Asthma and asthma-related phenotypes were analyzed using family-based association analyses. In the UK families, a...
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