Article
Fine mapping and single nucleotide polymorphism association results of candidate genes for asthma and related phenotypes.
Human mutation - 1 Oct 2001
Immervoll T, Loesgen S, Dütsch G, Gohlke H, Herbon N, Klugbauer S, Dempfle A, Bickeböller H, Becker-Follmann J, Rüschendorf F, Saar K, Reis A, Wichmann H E, Wjst M
Abstract excerpt
Several genome-wide screens for asthma and related phenotypes have been published to date but data on fine-mapping are scarce. For higher resolution we performed a fine-mapping study with 2 cM average spacing in often discussed asthma candidate regions (2p, 5q, 6p, 7p, 9q, 11p, and 12q) to narrow down the regions of interest. All participants of a Caucasian family study (97 families with at least two affected sib...
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