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Article

Association of defensin beta-1 gene polymorphisms with asthma.

The Journal of allergy and clinical immunology - 1 Feb 2005

Levy Hara, Raby Benjamin A, Lake Stephen, Tantisira Kelan G, Kwiatkowski David, Lazarus Ross, Silverman Edwin K, Richter Brent, Klimecki Walter T, Vercelli Donata, Martinez Fernando D, Weiss Scott T

Abstract excerpt

BACKGROUND: Defensins are antimicrobial peptides that may take part in airway inflammation and hyperresponsiveness. OBJECTIVE: We characterized the genetic diversity in the defensin beta-1 (DEFB1) locus and tested for an association between common genetic variants and asthma diagnosis. METHODS: To identify single nucleotide polymorphisms (SNPs), we resequenced this gene in 23 self-defined European Americans and...

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Identifiers

PMID: 15696078
DOI: 10.1016/j.jaci.2004.11.013
PMCID: PMC4475026

Genes

DEFB1
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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