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Article

Neuronal NO synthase (NOS1) is a major candidate gene for asthma.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 1999

Grasemann H, Yandava C N, Drazen J M

Abstract excerpt

Asthma is a common, but heterogeneous disease, characterized by reversible airway obstruction, bronchial hyperresponsiveness (BHR); and is commonly associated with atopy. The messenger molecule nitric oxide (NO), that is formed by neuronal NO synthase (NOS1), is known to have a key role in bronchomotor control in animals. In humans the gene for NOS1 is located on chromosome 12q24, in a region that had been shown...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10641565

Genes

NOS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Neuronal NO synthase (NOS1) is a major candidate gene for asthma.PMID 10641565Read ↗

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Single nucleotide polymorphisms in the NOS2 and NOS3 genes are associated with exhaled nitric oxide.Semantic proximity Read ↗

Exhaled nitric oxide in patients with asthma: association with NOS1 genotype.Semantic proximity Read ↗

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Nitric oxide synthase (NOS) single nucleotide polymorphisms are associated with coronary heart disease and hypertension in the INTERGENE study.Semantic proximity Read ↗

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