Article
Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients.
Journal of surgical oncology - 1 May 2007
Croitoru Marina E, Cleary Sean P, Berk Terri, Di Nicola Nando, Kopolovic Ilana, Bapat Bharati, Gallinger Steven
Abstract excerpt
OBJECTIVES: MYH is a member of the DNA base excision repair (BER) pathway and mutations of this gene predispose to the development of colorectal neoplasia in an autosomal recessive transmission pattern. Our objective was to determine the significance of MYH mutations in a series of Canadian patie...
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