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Article

Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study.

Gastroenterology - 1 Apr 2009

Cleary Sean P, Cotterchio Michelle, Jenkins Mark A, Kim Hyeja, Bristow Robert, Green Roger, Haile Robert, Hopper John L, LeMarchand Loic, Lindor Noralane, Parfrey Patrick, Potter John, Younghusband Ban, Gallinger Steven

Abstract excerpt

BACKGROUND & AIMS: The MutY human homologue (MYH) gene is a member of the base-excision repair pathway involved in the repair of oxidative DNA damage. The objective of this study was to determine colorectal cancer (CRC) risk associated with mutations in the MYH gene. METHODS: A total of 3811 CRC cases and 2802 controls collected from a multisite CRC registry were screened for 9 germline MYH mutations; subjects...

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Identifiers

PMID: 19245865
DOI: 10.1053/j.gastro.2008.12.050
PMCID: PMC2739726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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