Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In-depth haplotype analysis of ABCA1 gene polymorphisms in relation to plasma ApoA1 levels and myocardial infarction.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2004

Tregouet David-Alexandre, Ricard Sylvain, Nicaud Viviane, Arnould Isabelle, Soubigou Stéphane, Rosier Marie, Duverger Nicolas, Poirier Odette, Macé Sandrine, Kee Frank, Morrison Caroline, Denèfle Patrice, Tiret Laurence, Evans Alun, Deleuze Jean-Francois, Cambien Francois

Abstract excerpt

OBJECTIVE: By regulating the cellular cholesterol efflux from peripheral cells to high-density lipoprotein, the ABCA1 protein is suspected to play a key role in lipid homeostasis and atherosclerosis. Twenty-six polymorphisms of the ABCA1 gene were genotyped and tested for association with plasma levels of ApoA1 and myocardial infarction (MI) in the ECTIM study. METHODS AND RESULTS: In addition to single-locus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-I
Share to ATP Binding Cassette Transporter 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP-Binding Cassette Transporters

Share to Myocardial Infarction

Share to Northern Ireland

Share to Scotland

Source

Identifiers

PMID: 14962947
DOI: 10.1161/01.ATV.0000121573.29550.1a

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In-depth haplotype analysis of ABCA1 gene polymorphisms in relation to plasma ApoA1 levels and myocardial infarction.PMID 14962947Read ↗

Genetic variation in ABCA1 predicts ischemic heart disease in the general population.Semantic proximity Read ↗

Effect of ABCA1 mutations on risk for myocardial infarction.Semantic proximity Read ↗

Genetic variation in ABCG1 and risk of myocardial infarction and ischemic heart disease.Semantic proximity Read ↗

Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease.Semantic proximity Read ↗

The effect of ABCA1 gene polymorphisms on ischaemic stroke risk and relationship with lipid profile.Semantic proximity Read ↗

Haplotype analysis of the CYP8A1 gene associated with myocardial infarction.Semantic proximity Read ↗

Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population.Semantic proximity Read ↗

A novel haplotype in ABCA1 gene effects plasma HDL-C concentration.Semantic proximity Read ↗

Association of ATP-binding cassette transporter A1 gene polymorphisms with plasma lipid variability and coronary heart disease risk.Semantic proximity Read ↗

ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore.Semantic proximity Read ↗

A promoter variant of the ATP-binding cassette transporter A1 gene alters the HDL cholesterol level in the general Japanese population.Semantic proximity Read ↗

ABCA1 gene promoter DNA methylation is associated with HDL particle profile and coronary artery disease in familial hypercholesterolemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.