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Article

Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population.

Atherosclerosis - 1 Feb 2010

Frikke-Schmidt Ruth

Abstract excerpt

Epidemiological studies consistently demonstrate a strong inverse association between low levels of high-density lipoprotein (HDL) cholesterol and increased risk of ischemic heart disease (IHD). This review focuses on whether both rare and common genetic variation in ABCA1 contributes to plasma levels of HDL cholesterol and to risk of IHD in the general population, and further seeks to understand whether low...

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Source

Identifiers

PMID: 19596329
DOI: 10.1016/j.atherosclerosis.2009.06.005

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population.PMID 19596329Read ↗

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