Article
ARGON: Fast, Whole-Genome Simulation of the Discrete Time Wright-Fisher Process
2016-01-12
Abstract excerpt
<h4>Motivation</h4> Simulation under the coalescent model is ubiquitous in the analysis of genetic data. The rapid growth of real data sets from multiple human populations led to increasing interest in simulating very large sample sizes at whole-chromosome scales. When the sample size is large, the coalescent model becomes an increasingly inaccurate approximation of the discrete time Wright-Fisher model (DTWF). A...
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Identifiers and source
- Literature Corpus work
- c61e6e65-4f53-53d3-8577-8bc34ad9b9cc
- DOI
- 10.1101/036376